Tag Archives: depression

Essential Reads: Zuranolone for Postpartum Depression

In 2019, the Food and Drug Administration (FDA) approved brexanolone, marketed by Sage Therapeutics as Zulresso, as a treatment for postpartum depression (PPD).  As a neurosteroid, brexanolone represents a novel approach to the treatment of postpartum mood disorders.  One of the most exciting things about brexanolone is the rapidity of the response, with the initial… Read More »

Essential Reads: Measuring the Impact of Antenatal Depression on the Fetal Brain Using Neuroimaging

Previous studies have observed that the children of depressed mothers are more likely to have delays in cognitive development, worse school performance, higher rates of behavioral problems, and deficits in social-emotional regulation.  Children of depressed mothers are also more likely to experience adolescent depression.   Most studies have understood these vulnerabilities to neurodevelopmental problems and psychiatric… Read More »

Low-Dose Testosterone for Depression in Women: Does It Work?

In women, testosterone is produced by the ovaries in small amounts; however, levels of testosterone decline with age, independent of menopausal status. Low-dose testosterone has been used to improve sexual functioning in women with hypoactive sexual desire disorder.  In addition, other studies have shown that testosterone may improve fatigue and depressive symptoms.  However, these studies… Read More »